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chrisy · 04-17-2008, 12:03 PM

Hi,

I didn't have Tykerb with Xeloda (I did with Avastin) and of course, everyone ALWAYS responds individually.

That said, the most common side effects are rash and diarrhea. There is a lot of info from Brenda in Texas on dietary things you can do to ease the second one. Have you looked in the Herceptin/Tykerb forum?

My personal experience was, I took the Tykerb in the am and was on a higher dose in the trial than is typical. I had the big D (I still can't spell it!) about an hour after this - but not every day. Maybe once a week or so. Mine was easily controlled with Immodium.

I also had a rash - sort of like in high school - but not horrible.

I liked the freedom from IV that comes with oral treatments, and I felt better on Tykerb than on Herceptin.

Good luck on the new combo - as you know, this has worked really well for a lot of ladies on the board.

Chris

04-17-2008, 12:03 PM	#2
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Hi, I didn't have Tykerb with Xeloda (I did with Avastin) and of course, everyone ALWAYS responds individually. That said, the most common side effects are rash and diarrhea. There is a lot of info from Brenda in Texas on dietary things you can do to ease the second one. Have you looked in the Herceptin/Tykerb forum? My personal experience was, I took the Tykerb in the am and was on a higher dose in the trial than is typical. I had the big D (I still can't spell it!) about an hour after this - but not every day. Maybe once a week or so. Mine was easily controlled with Immodium. I also had a rash - sort of like in high school - but not horrible. I liked the freedom from IV that comes with oral treatments, and I felt better on Tykerb than on Herceptin. Good luck on the new combo - as you know, this has worked really well for a lot of ladies on the board. Chris __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure