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R.B. · 04-04-2008, 02:34 PM

Sherry683, I am sad to hear your news.

You said "He told my brother he might want to try a naturalistic approach. My brother is an auditor and much too logical to buy that,"

I am qualified Accountant too, slowly dessicated by all that dry work, and too logical and persistent for my own good on occasions, and as you may have noticed am convinced Omega 3s and 6s have a big role in health.

Please wish your brother well.

RB

Omega 3 Fatty Acids in Clinical Nutrition - [Heller Stehr Koch] - look at administration of DHA by lipid infusion.

There are Australian trials looking at lipid infusion and melanoma with cox blockers.

Here are some more results of a search below.

I have no expertise I am just posting these as potential lines of enquiry that you may wish to pursue with your medical advisor's.

http://www.oilofpisces.com/cancer.html

Docosahexaenoic acid halts melanoma
We do not usually report on animal or test tube experiments, but found the results of this study so intriguing that we decided to make an exception.

VALHALLA, NEW YORK. The incidence of cutaneous malignant melanoma is growing rapidly among persons with fair skin. It is estimated that one in 75 Americans will develop melanoma within their lifetime. Melanoma has a pronounced tendency to spread to other organs (metastasis) and the 5-year survival rate for metastatic melanoma is less than 10%. There is growing evidence that diet can influence the risk of developing melanoma. It is now believed that a high intake of omega-6 fatty acids stimulates the growth of melanoma and other cancers whereas omega-3 fatty acids suppress the growth of cancer cells.

Researchers at the New York Medical College and the American Health Foundation have just released the results of a laboratory experiment which clearly shows that docosahexaenoic acid (DHA), a main component of fish oil, is highly effective in inhibiting the growth of human melanoma cells. The researchers treated 12 different human metastatic melanoma cell cultures (in vitro) with DHA and found that more than 50% of them stopped growing. They urge further testing of their findings in full-scale clinical trials involving patients with melanoma. They conclude that “if DHA is capable of suppressing cell and tumor growth and metastatic potential in in vivo models of melanoma, a clinical trial of DHA would be warranted as an adjuvant to current surgical and chemotherapeutic interventions”.
Albino, Anthony P., et al. Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation. Cancer Research, Vol. 60, August 1, 2000, pp. 4139- 45

http://www.sciencedirect.com/science...1d30694d3cf073

http://linkinghub.elsevier.com/retri...60894X06002605

"A conjugate of DHA and doxorubicin (DHA–Dox) was synthesized, and its antitumor activity was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia and B16 melanoma. DHA–Dox showed a greatly improved antitumor efficacy compared to free doxorubicin."

http://www.informaworld.com/smpp/con...ent=a788043412
Human colon carcinoma COLO 205, carrying wild type p53, grown subcutaneously in athymic mice was inhibited 80% by a high fat menhaden oil diet containing a mixture of omega-3 fatty acids compared to the low fat corn oil diet containing omega-6 fatty acids. Feeding a high fat diet of golden algae oil containing docosahexaenoic acid (DHA) as the sole long chain omega-3 fatty acid resulted in 93% growth inhibition.

http://grande.nal.usda.gov/ibids/ind...&therow=388847

04-04-2008, 02:34 PM	#12
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Sherry683, I am sad to hear your news. You said "He told my brother he might want to try a naturalistic approach. My brother is an auditor and much too logical to buy that," I am qualified Accountant too, slowly dessicated by all that dry work, and too logical and persistent for my own good on occasions, and as you may have noticed am convinced Omega 3s and 6s have a big role in health. Please wish your brother well. RB Omega 3 Fatty Acids in Clinical Nutrition - [Heller Stehr Koch] - look at administration of DHA by lipid infusion. There are Australian trials looking at lipid infusion and melanoma with cox blockers. Here are some more results of a search below. I have no expertise I am just posting these as potential lines of enquiry that you may wish to pursue with your medical advisor's. http://www.oilofpisces.com/cancer.html Docosahexaenoic acid halts melanoma We do not usually report on animal or test tube experiments, but found the results of this study so intriguing that we decided to make an exception. VALHALLA, NEW YORK. The incidence of cutaneous malignant melanoma is growing rapidly among persons with fair skin. It is estimated that one in 75 Americans will develop melanoma within their lifetime. Melanoma has a pronounced tendency to spread to other organs (metastasis) and the 5-year survival rate for metastatic melanoma is less than 10%. There is growing evidence that diet can influence the risk of developing melanoma. It is now believed that a high intake of omega-6 fatty acids stimulates the growth of melanoma and other cancers whereas omega-3 fatty acids suppress the growth of cancer cells. Researchers at the New York Medical College and the American Health Foundation have just released the results of a laboratory experiment which clearly shows that docosahexaenoic acid (DHA), a main component of fish oil, is highly effective in inhibiting the growth of human melanoma cells. The researchers treated 12 different human metastatic melanoma cell cultures (in vitro) with DHA and found that more than 50% of them stopped growing. They urge further testing of their findings in full-scale clinical trials involving patients with melanoma. They conclude that “if DHA is capable of suppressing cell and tumor growth and metastatic potential in in vivo models of melanoma, a clinical trial of DHA would be warranted as an adjuvant to current surgical and chemotherapeutic interventions”. Albino, Anthony P., et al. Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation. Cancer Research, Vol. 60, August 1, 2000, pp. 4139- 45 http://www.sciencedirect.com/science...1d30694d3cf073 http://linkinghub.elsevier.com/retri...60894X06002605 "A conjugate of DHA and doxorubicin (DHA–Dox) was synthesized, and its antitumor activity was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia and B16 melanoma. DHA–Dox showed a greatly improved antitumor efficacy compared to free doxorubicin." http://www.informaworld.com/smpp/con...ent=a788043412 Human colon carcinoma COLO 205, carrying wild type p53, grown subcutaneously in athymic mice was inhibited 80% by a high fat menhaden oil diet containing a mixture of omega-3 fatty acids compared to the low fat corn oil diet containing omega-6 fatty acids. Feeding a high fat diet of golden algae oil containing docosahexaenoic acid (DHA) as the sole long chain omega-3 fatty acid resulted in 93% growth inhibition. http://grande.nal.usda.gov/ibids/ind...&therow=388847