HER2 Support Group Forums - View Single Post - AI induced bone and joint pain more common that reflected in clinical trials

TSund · 03-07-2008, 08:21 AM

THANK-YOU Lani!

As long as I have your attention, could you address this question of tamoxifen "UN-metabolizers" (sorry for the poor English) Do these studies that keep showing AI's with an advantage over tamoxifen take that percentage of women into account?

Ruth will probably switch anyhow to mute the possibility of endrometrial problems, but I am very leery of the sometimes severe side effects of the AI's. Ruth is a CPA and if she has trouble in her hands at the computer it would affect her job, and thus ultimately her health insurance.

THanks

Terri

03-07-2008, 08:21 AM	#9
TSund Senior Member Join Date: May 2007 Location: DFW area (TX) Posts: 431	THANK-YOU Lani! As long as I have your attention, could you address this question of tamoxifen "UN-metabolizers" (sorry for the poor English) Do these studies that keep showing AI's with an advantage over tamoxifen take that percentage of women into account? Ruth will probably switch anyhow to mute the possibility of endrometrial problems, but I am very leery of the sometimes severe side effects of the AI's. Ruth is a CPA and if she has trouble in her hands at the computer it would affect her job, and thus ultimately her health insurance. THanks Terri __________________ Terri, spouse of Ruth, Dallas/Ft. Worth area Ruth dx 05/01/07 (age 50) Filipino multifocal, several tumors .5 -2.5 cm, large area Breast MRI showed 2 enlarged nodes, not palpable 100%ER+, 95%PR+, HER2+++ 6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage 1 year Herceptin till 6/08 MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells" now 50% ER+, PR- ??? Rads finished 1/16/08 Added Tamoxifen, Finished Herceptin 05/08 NOW is the time to appreciate life to the fullest.