HER2 Support Group Forums - View Single Post - Success in overcoming herceptin resistance

eric · 02-20-2008, 06:14 AM

http://www.newsrx.com/library/topics...ancer/186.html

The researchers concluded: "The combination of trastuzumab and the mTOR inhibitor RAD001 also slowed breast cancer cell growth in vitro and in vivo Combining trastuzumab with inhibitors of the Akt/mTOR pathway is a clinically applicable strategy and combinations of trastuzumab with triciribine or RAD001 are promising regimens for rescue of trastuzumab resistance caused by PTEN loss."

02-20-2008, 06:14 AM	#1
eric Senior Member Join Date: Sep 2005 Posts: 589	Success in overcoming herceptin resistance http://www.newsrx.com/library/topics...ancer/186.html The researchers concluded: "The combination of trastuzumab and the mTOR inhibitor RAD001 also slowed breast cancer cell growth in vitro and in vivo Combining trastuzumab with inhibitors of the Akt/mTOR pathway is a clinically applicable strategy and combinations of trastuzumab with triciribine or RAD001 are promising regimens for rescue of trastuzumab resistance caused by PTEN loss."