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Old 02-12-2008, 09:09 AM   #1
Kim in DC
Senior Member
 
Join Date: Nov 2004
Posts: 190
Regional recurrence

I had a biopsy from my skin in my arm pit last week and it came back positive. I have been on herceptin/taxotere and herceptin/navelbine.I have been on herceptin alone since then. Are there any other combinations that are supposed to be synergistic with herceptin? Did anyone progress under the arm after lymph nodes were removed? The surgeon is saying that it is not necessarily skin mets but clogged lymph vessels similar to my ibc presentation. I will have scans this week. I'm praying that it is only regional.

Kim
__________________
8/98 dx right breast
5/2003 tram flap right breast
8/2004 dx new primary left breast with inflammatory bc
er/pr-, her2neu+++
8/19 taxotere and herceptin
1/15/2005 Navelbine/Herceptin
4/2005 radiation and Herceptin
5/15/2005 Herceptin alone
2/12/2008 skin biopsy positive
2/14/2008 met to sternum, possibly right breast
2/27/08 Start omitarg, herceptin, taxotere trial
3/17/08 Kicked off trial because I started too close to my last herceptin
3/19 start tykerb xeloda
Right breast confirmed met
5/15/08 skin mets gone, no hypermetabolic activity in breast, sternum healing
8/24/08 scans still look good. sternum still active with scarring. No evidence of progression
10/08 Progression in sternum
12/08 Start TDM1 trial
1/09 Scans show stable
12/09 1 year on TDM1 still stable
10/10 progression in chest and liver
11/10 false positive of liver mets; tykerb and herceptin
4/11 Tykerb/Herceptin/Xgeva
4/11 Rads to Sternum
5/12/12 NED Herceptin/Zometa
3/16/19 still NED Herceptin/Zometa very 6months
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