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Old 01-29-2008, 12:52 PM   #6
alw
Senior Member
 
Join Date: Apr 2006
Posts: 63
Sorry for the duplicate information - I posted at the same time as CPA. -Amy

I would guess the drug you are referring to in the clinical trial is E7389. There are a number of clinical trials involving E7389 and breast cancer - some recruiting and some active but not recruiting.

E7389 is a synthetic analog of halichondrin B (HB), which is a natural product shown in preclinical studies to have highly potent anti-cancer activity in vitro and in vivo. Halichondrin B was originally isolated from a type of marine sponge.

Here is one of Lani's posts regarding E7389 from SABCS from a few years ago. Maybe Lani or others will chime in if they see this.

http://her2support.org/vbulletin/sho...ighlight=e7389

-Amy
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