HER2 Support Group Forums - View Single Post - AC then T+Herceptin then hold the T(axol)?

Lolly · 01-18-2008, 03:36 PM

HI Melanie,
I don't think you should worry too much about getting another week off from Taxol; you are still receiving Herceptin, right?
I'm wondering if your onc has second thoughts on the Taxol given your sensitivity to it, and is considering Taxotere which is a reformulated version of Taxol that is less likely to cause a reaction.
There is evidence that taxanes are beneficial in reducing recurrence in HER2+, ER/PR- BC, so be sure and do your research before your next visit with your onc.
Beyond that I don't feel qualified to advise you, but here's a link to some earlier posts on the subject of Taxol use in HER2+, ER/PR-:

http://her2support.org/vbulletin/sho...erceptin+taxol

Hope this helps.

<3 Lolly

01-18-2008, 03:36 PM	#2
Lolly Senior Member Join Date: Aug 2001 Location: Oregon Posts: 1,756	HI Melanie, I don't think you should worry too much about getting another week off from Taxol; you are still receiving Herceptin, right? I'm wondering if your onc has second thoughts on the Taxol given your sensitivity to it, and is considering Taxotere which is a reformulated version of Taxol that is less likely to cause a reaction. There is evidence that taxanes are beneficial in reducing recurrence in HER2+, ER/PR- BC, so be sure and do your research before your next visit with your onc. Beyond that I don't feel qualified to advise you, but here's a link to some earlier posts on the subject of Taxol use in HER2+, ER/PR-: http://her2support.org/vbulletin/sho...erceptin+taxol Hope this helps. <3 Lolly __________________ Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation. Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.