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Standard protocol for Herceptin is one year. If your LVEF drops you are taken off Herceptin until such time that your LVEF comes back up. At that point you get another loading dose and can continue your year. there was a study that tested nine weeks of Herceptin. It was called the FINHER trial. Because of the small amount of women in the trial the doctors still rely on the year protocol. I know that there are currently studies comparing 6 months of Herceptin to 1 year. Herceptin is a relatively new drug and I don't think the doctors really know what the optimum amount of Herceptin is.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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