HER2 Support Group Forums - View Single Post - Tamoxifen Resistance in Her2+

Cathya · 01-10-2008, 11:22 PM

Ladies;

I am of the belief that with Her2+ bc one must not ever just use herceptin for one year. Because it is not an option for most to continue with early stage, I am a firm believer in using the Serum Her2 test along with other tumor markers on a regular basis to monitor for potential spread. As you ladies are so very young with "borderline" hormone positive disease I think this test would work better for you than for someone like me who is hormone positive....that is I have hormones driving my disease along with the her2 so it can get a little complicated. These blood tests are available and offer us an action plan to monitor our disease. I just heard today about a saliva test for breast cancer. Who knows, perhaps this can be used for the same purpose. My point is only that with herceptin available now, should tumor markers and serum her2 indicate something is happening, you can take herceptin to put a halt to it prior to tumors actually developing. This is the theory in any case.

Cathy

01-10-2008, 11:22 PM	#15
Cathya Senior Member Join Date: Sep 2005 Location: Ontario, Canada Posts: 752	Ladies; I am of the belief that with Her2+ bc one must not ever just use herceptin for one year. Because it is not an option for most to continue with early stage, I am a firm believer in using the Serum Her2 test along with other tumor markers on a regular basis to monitor for potential spread. As you ladies are so very young with "borderline" hormone positive disease I think this test would work better for you than for someone like me who is hormone positive....that is I have hormones driving my disease along with the her2 so it can get a little complicated. These blood tests are available and offer us an action plan to monitor our disease. I just heard today about a saliva test for breast cancer. Who knows, perhaps this can be used for the same purpose. My point is only that with herceptin available now, should tumor markers and serum her2 indicate something is happening, you can take herceptin to put a halt to it prior to tumors actually developing. This is the theory in any case. Cathy __________________ Cathy Diagnosed Oct. 2004 3 cm ductal, lumpectomy Nov. 2004 Diagnosed Jan. 2005 tumor in supraclavicular node Stage 3c, Grade 3, ER/PR+, Her2++ 4 AC, 4 Taxol, Radiation, Arimidex, Actonel Herceptin for 9 months until Muga dropped and heart enlarged Restarting herceptin weekly after 4 months off Stopped herceptin after four weekly treatments....score dropped to 41 Finished 6 years Arimidex May 2015 diagnosed with ovarian cancer Stage 1C started 6 treatments of carboplatin/taxol Genetic testing show BRCA1 VUS Nice! My hair came back really curly. Hope it lasts lol. Well it didn't but I liked it so I'm now a perm lady 29 March 2018 Lung biopsy following chest CT showing tumours in pleura of left lung, waiting for results to the question bc or ovarian April 20, 2018 BC mets confirmed, ER/PR+ now Her2- Questions about the possibility of ovarian spread and mets to bones so will be tested and monitored for these. To begin new drug Palbociclib (Ibrance) along with Letrozole May, 2018. Genetic testing of ovarian tumour and this new lung met will take months. To see geneticist to be retested for BRCA this week....still BRCA VUS CA125 has declined from 359 to 12 as of Aug.23/18