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R.B. · 01-09-2008, 04:48 PM

Jan 2008

"Fish oil rich in n-3 polyunsaturated fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protects inflammation induced bone loss in chronic inflammatory diseases like rheumatoid arthritis, periodontitis, and osteoporosis."

"Our findings suggest that DHA may be much more effective than EPA in alleviating RANKL induced proinflammatory cytokine production, intracellular signaling activation, thereby decreasing osteoclast activation and bone resorption."

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

J Cell Physiol. 2008 Jan;214(1):201-9.Click here to read Links
Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid.
Rahman MM, Bhattacharya A, Fernandes G.

Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA.

01-09-2008, 04:48 PM	#5
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Jan 2008 "Fish oil rich in n-3 polyunsaturated fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protects inflammation induced bone loss in chronic inflammatory diseases like rheumatoid arthritis, periodontitis, and osteoporosis." "Our findings suggest that DHA may be much more effective than EPA in alleviating RANKL induced proinflammatory cytokine production, intracellular signaling activation, thereby decreasing osteoclast activation and bone resorption." http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum J Cell Physiol. 2008 Jan;214(1):201-9.Click here to read Links Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid. Rahman MM, Bhattacharya A, Fernandes G. Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA.