HER2 Support Group Forums - View Single Post - does her2 gene amplifcn combine with oncoproteins from HPV infection 2 cause her2 BC?

Lani · 12-28-2007, 06:24 AM

that HPV without her2 amplification doesn't form tumors, that her2 without HPV contribution only seemed to cause DCIS withit taking the additional contribution from HPV to actually cause it to invade.

This was done in a petri-dish on cell lines and by genetically breeding abnormal mice. It is not necessarily the case in humans, but could be.

Can't help with your other request.

Hope this helped.

12-28-2007, 06:24 AM	#2
Lani Senior Member Join Date: Mar 2006 Posts: 4,783	the article says both contribute to causing invasive breast cancer-- that HPV without her2 amplification doesn't form tumors, that her2 without HPV contribution only seemed to cause DCIS withit taking the additional contribution from HPV to actually cause it to invade. This was done in a petri-dish on cell lines and by genetically breeding abnormal mice. It is not necessarily the case in humans, but could be. Can't help with your other request. Hope this helped.