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chrisy · 12-24-2007, 02:03 PM

Irene,

I've been thinking of you a lot, and how you are again searching for new solutions. Sounds like the Herceptin DM1 might be a possibility, and you certainly have access to the best doctors (including yours who seems endlessly creative and really works hard on your behalf). I heard a discussion in San Antonio on the H-DM1 in which the researcher was saying this agent was great against cancer but in the past it had been TOO TOXIC to use. Now attaching it to the Herceptin (like a guided missile) they could finally use it to benefit patients

I remember your post OVER a year and a half ago which I think was titled "running out of options". Followed by your pioneering with tykerb/xeloda which gave you a longer run than you'd seen in many years.

Here's hoping that you will find an even better weapon this time around.

Much love and many blessings to you, my friend.
Chris

12-24-2007, 02:03 PM	#5
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Irene, I've been thinking of you a lot, and how you are again searching for new solutions. Sounds like the Herceptin DM1 might be a possibility, and you certainly have access to the best doctors (including yours who seems endlessly creative and really works hard on your behalf). I heard a discussion in San Antonio on the H-DM1 in which the researcher was saying this agent was great against cancer but in the past it had been TOO TOXIC to use. Now attaching it to the Herceptin (like a guided missile) they could finally use it to benefit patients I remember your post OVER a year and a half ago which I think was titled "running out of options". Followed by your pioneering with tykerb/xeloda which gave you a longer run than you'd seen in many years. Here's hoping that you will find an even better weapon this time around. Much love and many blessings to you, my friend. Chris __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure