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runtolive · 12-24-2007, 07:23 AM

trastuzumab-dm1 from genentech.. its herceptin ..linked to a maytansine toxin.. its currently in a phase 2 trial being dosed at 3.6mg/kg..

at the SABC..san antonio breast cancer symposium.. genentech reported results on their phase 1 patients..

5 of 15 patients with MBC...metastatic breast cancer had a partial response.. and 7 of the remaining 10 pts.. had stable disease...

so 12 of 15 pts are no longer in danger of dying this year because of genentech... the trials are being run at over 30 sites nationwide.. so for women who have been on herceptin in the past and relapse..
THERE IS HOPE...

they are also running a second phase 1 escalation trial to see if weekly dosing is better than every 3 weeks.. some ladies on this board are in both studies and by all accounts.. are doing FANTASTIC...

12-24-2007, 07:23 AM	#3
runtolive Senior Member Join Date: Nov 2007 Posts: 210	u missed the most promising drug tdm1 trastuzumab-dm1 from genentech.. its herceptin ..linked to a maytansine toxin.. its currently in a phase 2 trial being dosed at 3.6mg/kg.. at the SABC..san antonio breast cancer symposium.. genentech reported results on their phase 1 patients.. 5 of 15 patients with MBC...metastatic breast cancer had a partial response.. and 7 of the remaining 10 pts.. had stable disease... so 12 of 15 pts are no longer in danger of dying this year because of genentech... the trials are being run at over 30 sites nationwide.. so for women who have been on herceptin in the past and relapse.. THERE IS HOPE... they are also running a second phase 1 escalation trial to see if weekly dosing is better than every 3 weeks.. some ladies on this board are in both studies and by all accounts.. are doing FANTASTIC...