[madubois63]

I was originally diagnosed stage IV (inflammatory bc) and had 3+ (active) nodes plus 2 nodes with dead cancer cells. I was her2+++ and er/pr+. I did not get Herceptin at that time. I had 4 years of remission. I am not sure what you mean by "...my hunch that it is mainly patients who might not think of themselves as high risk." I never think of myself as high risk, even after leukemia and my third bout with bc; but my original diagnosis made me high risk of dying and reoccurance from the beginning. I did receive Herceptin when I relapsed. I got a year and a half of treatment before I had to quit because of the leukemia diagnosis. I guess the year and a half of Herceptin was not enough, because the bc is back. I am presently waiting for pathology to come back. If things haven't changed and I am still Her2+, I may start Herceptin again. I guess I don't fit in to many categories any more and wouldn't be eligible for the trial, but thanks for posting...