[Margerie]

I am wondering how Her2 neu works here. Maybe this kind of cancer was so aggressive- (pre-herceptin) because the Her2 is found on normal cells and immune systems have a hard time recognizing the cancer cells even with strong Her2 neu expression.

Interesting- Mary Disis is one of the clinical researchers at U of W Her2 DNA Plasmid vaccine. They tested me for an immune response to the Her2neu protein (after chemo and during herceptin but before my first vaccine) and I had none. That is the usual case I understand. After 2 doses of the vaccine (3 in all) I had a measured immune response to the Her2 protein. They are still running assays on my follow up blood samples.