HER2 Support Group Forums - View Single Post - ER-/PR+ Tamoxifen effectiveness?

Becky · 11-15-2007, 08:55 PM

I have the opposite pathology (ER+/PR-) and Tamoxifen tends to work better if you are positive for both (and strongly positive). Since your situation is rarer than mine, I would discuss with your onc on the effectiveness of Tamoxifen in your situation or if Evista or Megace might be better. I will see if I have something to post in my virtual library on this. However, I would never stop taking the Tamoxifen without discussing with your onc and maybe even getting another opinion (medical opinion) of what you should do.

11-15-2007, 08:55 PM	#2
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	I have the opposite pathology (ER+/PR-) and Tamoxifen tends to work better if you are positive for both (and strongly positive). Since your situation is rarer than mine, I would discuss with your onc on the effectiveness of Tamoxifen in your situation or if Evista or Megace might be better. I will see if I have something to post in my virtual library on this. However, I would never stop taking the Tamoxifen without discussing with your onc and maybe even getting another opinion (medical opinion) of what you should do. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think" Last edited by Becky; 11-15-2007 at 09:07 PM..