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I had CAF (5 years ago, when that or CEF was the more common regimen, or CMF), and possibly steroids could be more necessary with the taxanes than with the regimen I had.
But the question still is, are we decreasing our risk with a chemotherapy but increasing it by adding drugs that influence weight gain and loss, if there is any significant amount of truth in the study that indicates that fluctuating weight puts one at higher risk? Maybe, just maybe, the effects on insulin are canceling out some of the benefit of doing chemo to some degree. I just think it is bizarre that until recently so much has been spent to develop toxic solutions to the problem and so little emphasis has been placed on understanding the endocrine system (other than thyroid problems or diabetes....)
A.A.
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