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Old 10-17-2007, 08:49 PM   #2
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Hi ,
First let me also say, your friend Jenny is lucky to have a friend like you for support.

My guess is that what is "next" is taxotere and carboplatin. That would be the typical power combo and a very reasonable treatment choice. I had taxol and carboplatin and found it very tolerable if you don't mind not having hair - which I did. The taxotere can cause problems with the nail beds; all the ladies in my infusion center put bags of frozen peas on their fingers and toes during the taxotere infusion - the office even had a little freezer to keep them in. That really helped. Overall, I think it is easier than the A/C (adriamycin/cytoxan) - that's what I hear.

Re Jenny's concerns with her team, it is actually becoming pretty common to have "neoadjuvant" chemo before surgery to try and reduce the tumor. So that need not necessarily be a concern.

Re the denial of recurrence, I can say I have some experience with that - I recurred to my liver after only having DCIS (stage 0 "precancer"). They were all in denial that it was the breast cancer. I think they have certain expectations, which are legitimate based on stats and their experience, and they naturally assume it is what they USUALLY would see. I know this is small consolation, but only 3 weeks of denial is pretty good and won't have made a difference in terms of treatment options.

She may very well be in good hands; however I would still recommend getting a 2nd opinion just based on the fact that she did have such an unusual (fast) recurrence. If she is not already seeing a top breast oncologist, I'd really suggest a consultation.

The rest of it, we all know. It sucks and even though it's just hair, for me it was a constant, visible reminder that all was NOT well. This is a tough road, but Jenny just needs to keep plugging away at it - and I know she will.

Good luck to you both. You are a good friend.

Chris
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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