HER2 Support Group Forums - View Single Post - Highly recommended video--do not miss the second half

Lani · 10-01-2007, 10:40 AM

ovaries have been hijacked for production of "vitamin H" (herceptin)

I believe Rituxan is also made from Chinese hamster ovaries now. It was only in the early days when they tried to make a different monoclonal antibody for EACH INDIVIDUAL PATIENT that they were using mice.

There are other interesting implications from this historical review on the development of monoclonal antibodies which perhaps extrapolate to her2+ breast cancer

10-01-2007, 10:40 AM	#4
Lani Senior Member Join Date: Mar 2006 Posts: 4,780	this video features an appearance of the predecessor of the Chinese hamster whose ovaries have been hijacked for production of "vitamin H" (herceptin) I believe Rituxan is also made from Chinese hamster ovaries now. It was only in the early days when they tried to make a different monoclonal antibody for EACH INDIVIDUAL PATIENT that they were using mice. There are other interesting implications from this historical review on the development of monoclonal antibodies which perhaps extrapolate to her2+ breast cancer