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Old 09-20-2007, 09:58 PM   #2
tousled1
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Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
Christine,

My oncologist has been giving me the HER2 Serum test every 12 weeks since it was FDA approved for advanced breast cancer. My tumor marker tests were never reliable. At dignosis of Stage IIIc my tumor marker was 15.3. It went as high as 30.1 during A/C treatment and then dropped back down to 15.1 where it is has has been since.

I feel that if it weren't for the HER2 Serum test I still would not know that I had lung mets. My baseline before starting Herceptin was 10.1. While on Herceptin it gradually decreased until it got to 6.3 where it stayed. Late June of this year when I had the HER2 serum test done it was up to9.5. My oncologist wasn't concerned since it was still below the normal of 15. I told her I didn't like that it went up so quick after stopping Herceptin (end of April). I was due for my annual brain MRI and she also ordered a CT of the chest, abdomen, and pelvis. Low and behold we found lung mets -- numberous nodules in both lungs but none larger than 1cm. Also found a 5mm brain nodule. If it weren't for the HER2 serum test my mets would have gone undected until such time as I developed symptoms.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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