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Dear Gary
You do not mention your wife's age. My period also came back and I had my ovaries removed to stay on Arimidex. AIs are proved superior if you are not highly ER+ and PR+. Your wife is PR+ but just moderately so. Highly positive is in the 70%+ range. Also, since she is only moderately + on at least PR, she is also Her2+ which is another indicator that an AI would work better. However, age does play a factor here too. I was 46 when I had my ovaries removed and would be 47 in a couple of months from then.
Lupron or Zoladex shots work well but are not as good as oophorectomy but it is an option in those under 40 or if you want to consider having a baby.
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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