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chrisy · 08-31-2007, 03:36 PM

Irene,
You never cease to amaze and impress me! Sounds like you are all set to not miss a beat should the scans show progression. Which, don't forget, is still not certain.

My pre-avastin BP was about the same as yours, averaging around 124/72. On avastin, I monitored it pretty closely at home and it crept up to high 130's/80's. Of course, at UCSF it was always higher (140's/90's) - a bit of "white coat" syndrome combined with the nearly 2 hour drive in rush hour traffic! So my doctor put me on a low dose (5 mg) lisinopril and yesterday in the infusion room it was 116/67! I've had no noticeable side effects from it.

Avastin is not a "hair challenging" treatment. Although after a year on Tykerb/Xeloda you may find going back to the infusion room cramps your style a bit! For me even going from 3 wk to 2 wk complicated my travel schedule LOL. But it is a short infusion, first 90 min, then 60, then 30 minutes.

It's a super easy combo (for me, anyway) and although I haven't seen any regression yet, it is keeping everything stable.

Keep us posted, Irene, and have a great weekend.

08-31-2007, 03:36 PM	#6
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Irene, You never cease to amaze and impress me! Sounds like you are all set to not miss a beat should the scans show progression. Which, don't forget, is still not certain. My pre-avastin BP was about the same as yours, averaging around 124/72. On avastin, I monitored it pretty closely at home and it crept up to high 130's/80's. Of course, at UCSF it was always higher (140's/90's) - a bit of "white coat" syndrome combined with the nearly 2 hour drive in rush hour traffic! So my doctor put me on a low dose (5 mg) lisinopril and yesterday in the infusion room it was 116/67! I've had no noticeable side effects from it. Avastin is not a "hair challenging" treatment. Although after a year on Tykerb/Xeloda you may find going back to the infusion room cramps your style a bit! For me even going from 3 wk to 2 wk complicated my travel schedule LOL. But it is a short infusion, first 90 min, then 60, then 30 minutes. It's a super easy combo (for me, anyway) and although I haven't seen any regression yet, it is keeping everything stable. Keep us posted, Irene, and have a great weekend. __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure