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Lani · 08-30-2007, 04:11 PM

from what I have read, so retesting of both her primary and her met may be in order. Triple negative breast cancer is often EGFR (her1)+ (so Iressa or Tarceva may be of help) and recent evidence shows some are exquisitely sensitive to cisplatin (heard this at a bc conference at the end of June). It seems Tykerb has not been helpful for those with only EGFR+ but her2- breast cancer according to most papers.

Hope some of this helped!

08-30-2007, 04:11 PM	#2
Lani Senior Member Join Date: Mar 2006 Posts: 4,782	her2+ breast cancer RARELY metastasizes as her2- from what I have read, so retesting of both her primary and her met may be in order. Triple negative breast cancer is often EGFR (her1)+ (so Iressa or Tarceva may be of help) and recent evidence shows some are exquisitely sensitive to cisplatin (heard this at a bc conference at the end of June). It seems Tykerb has not been helpful for those with only EGFR+ but her2- breast cancer according to most papers. Hope some of this helped!