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Old 08-30-2007, 12:52 AM   #4
Lani
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Join Date: Mar 2006
Posts: 4,783
it is an enzyme which acts as an antioxidant

and has now been found to suppress her2 neu overexpression, which is what makes her2neu+ breast cancer grow and metastasize.

In this article rather than referring to the enzyme (a protein product of a gene) they are referring to the gene for the enzyme specifically. When they use the word "transfected" they are talking about inserting the DNA for the gene into the her2+ breast cancer cell line--by doing so they could reduce the growth and metastatic ability of the cell line compared to the cell line which did not have the DNA for MnSOD inserted.

Hope this helps
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