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at conferences I have heard up to 6 months quoted
There was a paper with Pamela Klein as one of the authors regarding the fact that the metabolism/clearance rate difference between fast and slow metabolizers/clearers of the monoclonal antibody varies by as much as 43% in patients with metastatic breast cancer (never saw a paper for those with early breast cancer) so the result may vary person to person anyway.
Hope this helps.
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