[Gerri]

Hi Erin,

I have been on Tamoxifen for a little over a year but am struggling with making a decision of whether to stay on it until I am in menopause (I'm 53 and still premenopausal) or go for the injections to shut down my ovaries and switch to an AI. My concern is not regarding chemo brain (although I do have it to a slight degree), but whether or not Tamoxifen is effective in HER2+ bc after Herceptin is finished. The post by Lani "here we go again: How inexact ER status testing is!!!" has several links from others to research papers regarding tamoxifen resistance. I have printed out several of them and plan to present them to my onc in Sept. You may want to take a look and see if you would like to do the same. My onc didn't feel there was enough solid data out there supporting this but I am still going to bring these studies to her attention to see if she changes her mind. She is leaving the decision up to me but I want to make sure I have enough info to support my decision.

Would love to hear what your onc has to say. Please keep me posted.

Thanks,