Thread: I Am So Upset
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Old 07-08-2007, 02:43 PM   #22
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
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You can do this

Oh Flori, I can feel how broken hearted you are. I know this is a huge disappointment for you, and I can tell how much you don't want to go back to a heavier chemo. At the same time, the fact that you are so hungry for your "normal" life says that you are hungry for life, period. You are a fighter and much as you don't want to, I know you will get suited up and back in the saddle fighting with everything you've got.

I agree with StephN, might be a good idea to get another biopsy if you can, these nasty little buggers can change their personalities and you want to know for sure what you're dealing with.

Staying on the Tykerb and adding stronger agents makes sense. Although data with Tykerb is of course limited, it is proven that adding chemo back to Herceptin gives new synergy; it seems likely this would be the case with Tykerb as well. I had carboplatin with Taxol and Herceptin and even with the taxol, it wasn't so bad. Except of course, the hair thing, which is SO distressing even though we know it is just hair.

Remember, the chemos are there to bring out bigger guns, get this stuff under control quicker. Maybe this combo will be just the ticket. Try to imagine it as a flow of lovely healing energy.

And remember, we love you very much. I am sending healing thoughts, wrapping you in this love right now.

Hang in there.

Much love
Chris
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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