HER2 Support Group Forums - View Single Post

Lolly · 07-05-2007, 09:32 PM

Eric, when I was on Herceptin and in and out of NED, my onc would always suggest reverting back to weekly Herceptin when it became necessary to combine it with chemo for that one-two punch that would hopefully knock me back into NED or stable disease...
I never had a triplet combo, because he feels the side effects are indeed more severe than with a single chemo. I had very good results from this strategy, and now that I'm on Tykerb/Abraxane the plan remains in place; use of single chemo's with Tykerb as necessary.
I don't know specifically about Taxotere side effects as that's one I've never had yet, but I know others here have info on that. I just wanted you to know I'm thinking of you and Caryn and to reassure you that a single chemo/Herceptin combo can be very effective and extend options.

<3 Lolly

07-05-2007, 09:32 PM	#3
Lolly Senior Member Join Date: Aug 2001 Location: Oregon Posts: 1,756	Eric, when I was on Herceptin and in and out of NED, my onc would always suggest reverting back to weekly Herceptin when it became necessary to combine it with chemo for that one-two punch that would hopefully knock me back into NED or stable disease... I never had a triplet combo, because he feels the side effects are indeed more severe than with a single chemo. I had very good results from this strategy, and now that I'm on Tykerb/Abraxane the plan remains in place; use of single chemo's with Tykerb as necessary. I don't know specifically about Taxotere side effects as that's one I've never had yet, but I know others here have info on that. I just wanted you to know I'm thinking of you and Caryn and to reassure you that a single chemo/Herceptin combo can be very effective and extend options. <3 Lolly __________________ Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation. Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.