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Becky · 07-05-2007, 08:23 AM

Dear Eric
I am sorry that Xeloda/Tykerb didn’t work for Caryn. None the less, Xeloda is not an effective drug for many women and by no means should you give up hope on this. It is very apparent however that a taxane with Herceptin did the trick before. Perhaps the weekly schedule dosing of Abraxane with Herceptin will work well. Lolly is using Abraxane (weekly) with Tykerb and it is going well too. You cannot make the assumption that Herceptin stopped working (just because when Caryn was using it alone she started to progress), she just needed alittle chemo assistance to help push it back again. You have tons of options left but a taxane worked well the first time!
<O

Also – what did you mean by “failure” – a lot of progression or just stable with no reduction of tumor load?
<O

I am thinking about you and if I come up with anything else, I’ll write. Big hug to you

07-05-2007, 08:23 AM	#11
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Dear Eric I am sorry that Xeloda/Tykerb didn’t work for Caryn. None the less, Xeloda is not an effective drug for many women and by no means should you give up hope on this. It is very apparent however that a taxane with Herceptin did the trick before. Perhaps the weekly schedule dosing of Abraxane with Herceptin will work well. Lolly is using Abraxane (weekly) with Tykerb and it is going well too. You cannot make the assumption that Herceptin stopped working (just because when Caryn was using it alone she started to progress), she just needed alittle chemo assistance to help push it back again. You have tons of options left but a taxane worked well the first time! <O Also – what did you mean by “failure” – a lot of progression or just stable with no reduction of tumor load? <O I am thinking about you and if I come up with anything else, I’ll write. Big hug to you __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"