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Hello,
You didn't mention what stage your husband is, or if the recommendation is for Herceptin as a single agent as adjuvant treatment for early stage or in conjunction with chemo. If you could share a little more info people may be able to be more helpful.
The "normal" schedule for Herceptin was originally weekly, later studies showed that the 3-week dose and schedule was as effective and many prefer this because it's easier to have a normal life between treatments.
I had herceptin weekly WITH taxol and carboplatin, then went on the 3 week schedule. What side effects I had I really attribute to the chemo rather than the Herceptin. I do know that once I finished the chemo and was on Herceptin alone, I felt much better!
In terms of effectiveness, I had a complete response to the T/C/H and then the Herceptin kept me in remission for another 2 years. So it is good stuff!
Everyone responds differently, but for me the T/C/H
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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