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And it may be that us TOPO2-neg people had a worse prognosis BECAUSE we were given anthracyclines and so often got a chemo that wouldn't help us. And with TCH or other chemo combos, maybe that prognosis is improved. Sounds reasonable to me. But this is simply my hypothesis.... not even bounced off my onc (*smile*).
Janet
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Janet in Rowlett Texas
Dx July 2006 IDC 1.8cm, ER-/PR- HER2+ (FISH 7), KI67 High (60%) grade 3, TOPO II neg
Aug2006: lumpectomy, SNB (4 nodes neg), Stage 1
Jan 2007: Finished 6 cycles of TCH (Taxotere, Carboplatin, Her ceptin). Then Herceptin every 3 weeks.
Feb 2007: Completed Radiation
May 2007: Stopped Herceptin due to low LVEF (49%)
July 2007: LVEF now 44% -- starting Coreg
May 2008: Heart NORMAL! Yippee.
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