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Becky · 06-24-2007, 06:24 PM

Just to shake this thread up a bit... it can all work until mutation takes place or there are some cells in a tumor that are Grade 1 - aka - almost like normal cells. Then what. Just because a tumor is Grade 2 or 3 doesn't mean ALL the cells are... If your tumor is 50% ER+ it means 50% of the cells have too many Estrogen receptors - not all the cells. Therefore, most cancer cells might need glucose (and lots of it) or lots of the insulin that the glucose makes the body secrete. Maybe other cells in the tumor LOVE corn oil. So, the glucose lovers die but the others survive (are resistant to your lack of sugar attempt) and those that survive do tend (in my research) be the slower to divide (and therefore more resistant to therapy of any kind because therapies (chemo, radiation etc) kill the fast to divide types... maybe the shear theory behind any resistance.

Comments? I hope so.

06-24-2007, 06:24 PM	#21
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Just to shake this thread up a bit... it can all work until mutation takes place or there are some cells in a tumor that are Grade 1 - aka - almost like normal cells. Then what. Just because a tumor is Grade 2 or 3 doesn't mean ALL the cells are... If your tumor is 50% ER+ it means 50% of the cells have too many Estrogen receptors - not all the cells. Therefore, most cancer cells might need glucose (and lots of it) or lots of the insulin that the glucose makes the body secrete. Maybe other cells in the tumor LOVE corn oil. So, the glucose lovers die but the others survive (are resistant to your lack of sugar attempt) and those that survive do tend (in my research) be the slower to divide (and therefore more resistant to therapy of any kind because therapies (chemo, radiation etc) kill the fast to divide types... maybe the shear theory behind any resistance. Comments? I hope so. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"