[Jean]

Karen, Janet, and Lala,
Yes the TOPO 11 is used to test for response to Anthracycines.

Dr. Slamon ordered the test - a tumor paraffin slide was sent out
to his lab in Calif. (this is not an exspecnsive test a little over $250).

You will need to go to the hospital where you had your surgery and request that a paraffin embedded tissue block to be sent for sectioning.
The block will be returned after the sections are cut. Also will need to
send a pathology report as well. If a block is not available, then send approzimately 5-6 unstained sections on plus slides cut 3-4 microns thick.

The following is the Dr. that Dr. Slamon used:

Dr. Michael Press
USC/Norris Cancer Center
1441 Eastlake Ave. STE 5409
Los Angeles, Ca. 90033-0800
phone 323-865-0563

I am TOPO 11 negative...I am glad that I saw Dr. Slamon who is always
on the cutting edge of treatment...most dr. do not even know about
the test or otherwise do not believe it has any value. With the newer
treatments available we can save ourselves heart damage esp. if TOPO 11 negative
where you may not obtain the best benefits from the treatment.

Good Luck and of course if I can help further just reach out.

Hugs,
Jean