HER2 Support Group Forums - View Single Post - Original Stage I's with high KI-67 that progressed?

Hopeful · 06-07-2007, 05:13 AM

Grace,

Here is a link to an article I posted about a mega analysis of KI-67 in the articles forum: http://her2support.org/vbulletin/sho...rid=1173<br />

Different studies use different cut-off points for different purposes. The lowest cut-off point I have seen is 10% for "positive." The author of the article says that is probably a good cut-off point for consideration of chemotherapy (i.e., below 10% and the returns on toxicity are greatly diminished). My Ki-67 was 11%, described as "borderline" on my path report. It did weigh into my decision to skip chemo.

Hopeful

06-07-2007, 05:13 AM	#11
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Grace, Here is a link to an article I posted about a mega analysis of KI-67 in the articles forum: http://her2support.org/vbulletin/sho...rid=1173<br /> Different studies use different cut-off points for different purposes. The lowest cut-off point I have seen is 10% for "positive." The author of the article says that is probably a good cut-off point for consideration of chemotherapy (i.e., below 10% and the returns on toxicity are greatly diminished). My Ki-67 was 11%, described as "borderline" on my path report. It did weigh into my decision to skip chemo. Hopeful