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Harrie,
I didn't have any discoloration of my nails, either fingers or toes, during treatment. I finished Herceptin last month and the nail on my big toe (right foot) started to feel funny. Lo and behold - it fell off. It is growing back but I found it very strange that it took that long for any of my nails to come off. I did have dry brittle nails that peeled the entire time I was in treatment. Guess everyone reacts differently.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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