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Shayan,
Many people respond well to Tykerb, and I hope your mother is one who does. If she doesn't, my sister has been taking the oral chemotherapy combination of Temodar(sm.molecule crosses BBB) and Sorafenib(an antiangiogenesis drug) and that Rx seems to be inhibiting new lesions from appearing. My sister also has had WBR, but even so, she was still able to receive numerous CyberKnife focalized radiation treatments for small mets, and growth was arrested.
She is feeling well with her current therapy, with minor/manageable side effects, and also receives Herceptin infusions every 3 weeks.
Best wishes to you and your Mom.
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