Hi Ragini, it's good to "see" you again 
I just started weekly Abraxane 3 weeks ago, and haven't felt too bad. It can cause nausea so I'm given Zofran prior to the Abraxane and so far have had no trouble other than my stomach feeling "funny" the night of treatment, slight headace for a couple of days, and tiredness. The Zofran causes constipation but that's manageable too. I can honestly say it's been pretty easy so far.
Hope this helps, to know there are other protocols besides the 3 weekly!
<3 Lolly
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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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