HER2 Support Group Forums - View Single Post - her2 breast cancer cured (when transplanted in mice) using triple targetted therapy

fullofbeans · 05-07-2007, 07:49 PM

Lani and all,

I simply cannot get this post out of my mind! Basically it seems so logical in principle to attack all possible pathways at once. I have always considered a cancer cell to be the equivallent of a 'pest' and the only way to deal with a pest is to go hard on it first time round, as to not allow it to develop resistance.

Anyhow, you said "for the activists among us, let's try to use our energies to help push this progress forward!". How can we push these things forward???? as mentioned in 2004 they had already published about the great results of combinaisons of drugs (either er+ or not the principle was already established) was working but nothing much was done since..

I have also noticed that unfortunatly that they may consider trial to take place for herceptin virgin only..does that mean that they would leave all of us behind! [how about lapatinib+gefinitib and pertuzumab]

I think that slowing the growth of cancer enough to allow your immune system to deal with it is the way forward.

I feel a need to get involved here.. So how can we push things forwards???

05-07-2007, 07:49 PM	#20
fullofbeans Senior Member Join Date: Jan 2007 Location: UK Posts: 617	Lani and all, I simply cannot get this post out of my mind! Basically it seems so logical in principle to attack all possible pathways at once. I have always considered a cancer cell to be the equivallent of a 'pest' and the only way to deal with a pest is to go hard on it first time round, as to not allow it to develop resistance. Anyhow, you said "for the activists among us, let's try to use our energies to help push this progress forward!". How can we push these things forward???? as mentioned in 2004 they had already published about the great results of combinaisons of drugs (either er+ or not the principle was already established) was working but nothing much was done since..<!-- / message --> I have also noticed that unfortunatly that they may consider trial to take place for herceptin virgin only..does that mean that they would leave all of us behind! [how about lapatinib+gefinitib and pertuzumab] I think that slowing the growth of cancer enough to allow your immune system to deal with it is the way forward. I feel a need to get involved here.. So how can we push things forwards??? __________________ 35 y/o June 06: BC stage I Grade 3; ER/PR neg Her-2+++; lumpectomies Aug 06: Stage IV liver mets: 6 tumours July 06 to Jan 07: 2FEC+6Taxotere; 3*TACE; LITT March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle). Herceptin since 2006 NED til Oct 09 Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised.. Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo.. superior vena cava blocked: stent but face remains puffy April 2012: Teresa Trial, randomised to TDM1 Nov 2012 progressing on TDM1 Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes. Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor. 'Under no circumstances should you lose hope..' Dalai Lama