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Becky · 05-04-2007, 06:52 PM

It is well known that Taxol is a great drug for Her2+ breast cancer. It is also a drug that works very synergistically with Herceptin. About half the Stage 1 women on this board have had AC followed by Taxol/Herceptin and half had 4 AC followed by Herceptin. Both regimes used Herceptin for a year. Another chemo option that many Stage 1 women (and higher stages) get is Taxol (or Taxotere), Carboplatin and Herceptin (6 rounds) then continuing herceptin for a year.

Whether or not you should receive Taxol is an opinion but studies on Stage 2 women (those with 1-4 nodes positive) has shown a marked decrease in recurrence if Taxol is used when trialed as 6 AC or 4 AC followed by 4 taxol (prior to dense dose and prior to using Herceptin). So, using a taxane is a survivability boost.

Certainly you should at least use Herceptin for a year as most Stage 1 protocol is 4 AC followed by a year of Herceptin.

I hope this helps

05-04-2007, 06:52 PM	#5
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	It is well known that Taxol is a great drug for Her2+ breast cancer. It is also a drug that works very synergistically with Herceptin. About half the Stage 1 women on this board have had AC followed by Taxol/Herceptin and half had 4 AC followed by Herceptin. Both regimes used Herceptin for a year. Another chemo option that many Stage 1 women (and higher stages) get is Taxol (or Taxotere), Carboplatin and Herceptin (6 rounds) then continuing herceptin for a year. Whether or not you should receive Taxol is an opinion but studies on Stage 2 women (those with 1-4 nodes positive) has shown a marked decrease in recurrence if Taxol is used when trialed as 6 AC or 4 AC followed by 4 taxol (prior to dense dose and prior to using Herceptin). So, using a taxane is a survivability boost. Certainly you should at least use Herceptin for a year as most Stage 1 protocol is 4 AC followed by a year of Herceptin. I hope this helps __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"