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Hi, good question. I was diagnosed in 2001, details in signature below. I desperately wanted Herceptin, which at that time was available for adjuvant use only in trials unless one was independently wealthy. I enrolled in NSABP B-31's adjuvant Herceptin trial and lost the toss - was randomized to the control (no Herceptin) arm. It was a hard blow at the time but here I am, six years later and NED.
Debbie L.
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3/01 ~ Age 49, occult primary announced by large axillary node found by my husband. Multiple CBE's, mammogram, U/S could not find anything in the breast. Axillary node biopsy - pathology said + for "mets above diaphragm, probably breast".
4/01 ~ Bilateral mastectomies (LMRM, R simple) - 1.2cm IDC was found at pathology.
5 of 11 axillary nodes positive, largest = 6cm. Stage IIIA
ERPR 5%/1% (re-done later at Baylor, both negative at zero).
HER2neu positive by IHC and FISH (8.89).
Lymphovascular invasion, grade 3, 8/9 modified SBR.
TX: Control of arm of NSABP B-31's adjuvant Herceptin trial (no Herceptin): A/C x 4 and Taxol x 4 q3weeks, then rads. Arimidex for two years, stopped after second patholgy opinion.
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