HER2 Support Group Forums - View Single Post - for those still wondering where the PR status fits into all this...

AlaskaAngel · 04-25-2007, 10:01 AM

Interesting, Hopeful -- thanks for posting.

I wonder what the percentage for the prevalence in the human population is for each type of bc mentioned.

If it does occur for T47-D cells, but as noted, "The induction of VEGF by progestins is also cell type specific and does not occur in human breast cancer cell lines MCF-7, ZR-75, or MDA-MB-231, nor in Ishikawa cells derived from a human endometrial carcinoma" then unless T47-D cells are quite prevalent in the human population, maybe progesterone has no negative effect on the majority of bc?

AlaskaAngel

04-25-2007, 10:01 AM	#10
AlaskaAngel Senior Member Join Date: Sep 2005 Location: Alaska Posts: 2,018	a contrarian speaks Interesting, Hopeful -- thanks for posting. I wonder what the percentage for the prevalence in the human population is for each type of bc mentioned. If it does occur for T47-D cells, but as noted, "The induction of VEGF by progestins<SUP> </SUP>is also cell type specific and does not occur in human breast<SUP> </SUP>cancer cell lines MCF-7, ZR-75, or MDA-MB-231, nor in Ishikawa<SUP> </SUP>cells derived from a human endometrial carcinoma" then unless T47-D cells are quite prevalent in the human population, maybe progesterone has no negative effect on the majority of bc? AlaskaAngel