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As far as a possible cholesterol/bc connection we can go down 2 paths.
One is that cholesterol is the precursor to the manufacture of all sex hormones (estrogen, progesterone, androgens). It is one of the reasons the body manufactures cholesterol. Therefore, you could possibly make some sort of conclusion that more cholestrol, more estrogen etc. However..
before hormones are made, first prostagladins are made (and then the sex hormones are made from that). Well, if you get into all that RB has been teaching us on omega 3s and omega 6s, these fats feed into that pathway. Prostaglandins cause inflammation (which isn't a bad thing in general but can be bad if it is ongoing. For example, pain comes from an inflammatory response. It is a good thing so that you know you are hurt or sick but a bad thing if it goes on forever. Because long term inflammation causes tissue damage. Tissue damage can cause changes in tissue DNA (ie dysplasia or cancers).
So, some of these pathways can definitely be involved. You can see how complex it all is - even the cancer cell in general. Its just amazingly complex and formidable!!!
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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