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This Australian group of researchers has done a lot of interesting work on vitamin E succinate in the lab.
For human applications at least two possible problems must be clarified:
1. In vivo it has been shown that ingested vitamin E succinate is split loosing its succinyl end. This might be the reason why most in vivo experiments rely on injection intead of oral consumption for optimal activity.
2. some of the Australian researchers have in previous in vivo animal studies demonstrated that injected vitamin E succinate is converted into regular vitamin E (alpha tocopherol) in the liver.
The difference between the two vitamins is that the latter is an antioxidant while the former is not.
So the mode of action of vitamin E succinate could be quite different in the body depending on location.
This brings back to the controversy about using antioxidants concurrently with cancer treatments such as chemo & radiotherapy.
For those interested Ralph Moss has published a long essay in favor of antioxidants as a reaponse to a review against their use by an M.D.
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