HER2 Support Group Forums - View Single Post - Can you think of Her2+ questions for Dr. Pegram?

dlaxague · 04-09-2007, 06:50 AM

Hi Barbara,

I'd like to know if Dr. Pegram is aware of any research, either completed or planned, that looks at prognosis and response based on the actual numbers of the FISH ratio, rather than simply positive and negative for HER2neu. There seems to be more interest (finally) in quantification of ERPR r/t to same. I wonder how they decided what the cutoff is, for FISH numbers?

Tell him thanks for whatever he has time to answer, and thanks to you, too, for offering to do this.

Debbie Laxague

04-09-2007, 06:50 AM	#15
dlaxague Senior Member Join Date: May 2006 Posts: 221	FISH value question Hi Barbara, I'd like to know if Dr. Pegram is aware of any research, either completed or planned, that looks at prognosis and response based on the actual numbers of the FISH ratio, rather than simply positive and negative for HER2neu. There seems to be more interest (finally) in quantification of ERPR r/t to same. I wonder how they decided what the cutoff is, for FISH numbers? Tell him thanks for whatever he has time to answer, and thanks to you, too, for offering to do this. Debbie Laxague