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caya · 04-05-2007, 10:58 AM

Thanks for that information about HER2+ cancer typically being negative for BRCA 1 & 2. I just got tested last week, and the genetics counsellor told me that based on my family history (spotty) and the fact that I am a premenopausal Jewish Ashkenazi woman under 50, my chances ( from a computer program) of having either of these genes is around 15%. Certainly hope I'm in the 85% NO group, as I have two daughters - 18 and 21.

She (and my onc.) told me that even if I am negative for the BRCA 1 & 2, my girls and my mother have double the risk of the normal population because there is probably another BC gene out there not yet discovered. So they will have to be more vigilant with earlier testing etc.

I will find out in about 4 months. I have an appointment next week with a gync. onc. to talk about ovary removal anyways.

Caya

04-05-2007, 10:58 AM	#9
caya Senior Member Join Date: Jan 2007 Location: Thornhill, Ontario Canada Posts: 2,320	Thanks for that information about HER2+ cancer typically being negative for BRCA 1 & 2. I just got tested last week, and the genetics counsellor told me that based on my family history (spotty) and the fact that I am a premenopausal Jewish Ashkenazi woman under 50, my chances ( from a computer program) of having either of these genes is around 15%. Certainly hope I'm in the 85% NO group, as I have two daughters - 18 and 21. She (and my onc.) told me that even if I am negative for the BRCA 1 & 2, my girls and my mother have double the risk of the normal population because there is probably another BC gene out there not yet discovered. So they will have to be more vigilant with earlier testing etc. I will find out in about 4 months. I have an appointment next week with a gync. onc. to talk about ovary removal anyways. Caya __________________ ER90%+/PR 50%+/HER 2+ 1.7 cm and 1.0 cm. Stage 1, grade 2, Node Negative (16 nodes tested) MRM Dec.18/06 3 x FEC, 3 x Taxotere Herceptin - every 3 weeks for a year, finished May 8/08 Tamoxifen - 2 1/2 years Femara - Jan. 1, 2010 - July 18, 2012 BRCA1/BRCA2 Negative Dignosed 10/16/06, age 48 , premenopausal Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so. Reclast infusion January 2012 Oopherectomy October 2013 15 Years NED!!