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Jean · 03-06-2007, 09:41 PM

PTEN alteration plays a direct role in her2 tumors?
I have read theire is a connection however I thought it is
still tangential. I thought it was still being tested at
MD Anderson? I would also like to have the test performed
but what drug is there to target the PI-3 Kinase/PTEN pathway
for those that are negative?

Thanks,
Jean

03-06-2007, 09:41 PM	#2
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	Is the data in that says PTEN alteration plays a direct role in her2 tumors? I have read theire is a connection however I thought it is still tangential. I thought it was still being tested at MD Anderson? I would also like to have the test performed but what drug is there to target the PI-3 Kinase/PTEN pathway for those that are negative? Thanks, Jean __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006