[Andi]

I have been on Navelbine/Herceptin weekly for lung mets since the beginning of January. I get the fatique from the Navelbine. It can be hard on the white blood counts, which it has for me. Because that makes my immune system really fragile, I have had some stomach issues at times, no nausea or diahrea, more like a good old fashioned belly ache. On the 16th of Feb, my whites were dropping, so they reduced the amount of Navelbine, but still gave it to me, the following week they went too low, so they just gave me herceptin.(which I do not receive any pre-meds with) March 2 I went in and had a chest xray as well as blood tests. The chest xray showed that my lesions are continuing to shrink and my blood counts were back up so I could have the Navelbine again. I went into this regimine right after having surgery, but the week I was off of the Navelbine, I could really tell how much it had really made me tired. I had so much extra energy that week. When I was on herceptin alone following my initial diagnosis, I had more hot flashes, runny/crusty nose, thin fingernails and my ankles would be stiff when I first got up, but after a few steps it would go away. I was off herceptin for about 3 months and the hot flashes went almost completely away, as did the nose and ankle issues. My fingernails remain very thin and now that I have started back on the herceptin, the other symptoms have returned, but I feel it is a small price to pay for keeping those cancer cells at bay. Good luck to you, and I hope you will tolerate your treatments.