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Cindy,
I was diagnosed post-menopause, triple positive, so went on AI's from the start. I began with Femara and developed severe tinnitus (ringing in the ears). My onc switched me to Arimidex, and I still have the tinnitus, but not as bad. I noticed some occasional joint pain, mostly in my hands, from Arimidex, but nothing that would make me stop the med. All told, I have been on AI's since October 1, 2006, and have had no problems with weight gain or additional hair thinning. As to "fuzzy brain," I can't blame either the cancer or the treatment for that - I think it is menopause and predates diagnosis.
Best of luck to you with your treatment,
Hopeful
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