HER2 Support Group Forums - View Single Post - HER2/neu role in breast cancer: from a prognostic foe to a predictive friend.

Lani · 01-31-2007, 07:52 PM

while reviewing the full article I found the following which might be helpful to Stephanie, Christine and others:

It referred to an article by Kirsch et al.which analyzed retrospectively 91 patients with brain metastases from breast cancer; 45 patients had tumors that did overexpress HER2; 35 of these women received trastuzumab and found that patients with HER2-overexpressing breast cancer had a significantly longer OS (median 23 compared with 10 months, P = 0.0016) after the development of brain metastases than patients who were HER2 negative.

And the pioneering women of this board are pushing the envelope farther and farther along! Wait 'til their stats make it into the literature

01-31-2007, 07:52 PM	#5
Lani Senior Member Join Date: Mar 2006 Posts: 4,783	Rhonda H while reviewing the full article I found the following which might be helpful to Stephanie, Christine and others: It referred to an article by Kirsch et al.which analyzed retrospectively 91 patients with brain metastases from breast cancer; 45 patients had tumors that did overexpress HER2; 35 of these women received trastuzumab and found that patients with HER2-overexpressing breast cancer had a significantly longer OS (median 23 compared with 10 months, P = 0.0016) after the development of brain metastases than patients who were HER2 negative. And the pioneering women of this board are pushing the envelope farther and farther along! Wait 'til their stats make it into the literature