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Her-2/neu: CEF-17 ratio: 7,8:1
Average her-2/neu count per cell 15.6
Mamimum her-2/neu count per cell 22
Average CEP-17 count per cell: 2.0
Cells counted: 25
The way I read it... they evaluated 25 cancer cells. The average HER-2/neu count was 15.6 per cell. Divide your average HER-2 by the average CEP-17 gives you the ratio. 15.6/2.0 is 7.8. So your ratio is 7.8:1. Anything over 2 is an overexpression of HER-2. (The max HER-2 they saw on any one cell was 22.)
I do not know the relationship between this and the Ki-67 score.
Skeetur
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12/01/2006 Initial Dx via stereotactic biopsy - DCIS, grade 3
12/27/2006 Lumpectomy w/ SNB: 2 foci of IDC (largest .3 cm, Grade 2, Notthingham score 6) amid large area of DCIS: No clear margins on the DCIS; re-excision recommended
ER+(55%)/PR+(60+)/HER2+ (2.8+ via IHC?)
01/23/2007 Re-excision Lumpectomy: No clear margins on the DCIS; mastectomy recommended
03/02/2007 Bilateral mastectomy w/ expander implant insertion
03/19/2007 Emergency surgery to fix broken blood vessel in left breast
03/30/2007 Met w/ oncologist; oncologist checking on HER2 status with pathologist and doing some consulting on my case - no treatments for now!
05/02/2007 Next appointment w/ oncologist
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